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Mosquitos can evolve shortly so it becomes a balancing act of killing them before the Plasmodium they carry becomes the infectious disease, but not so quick that they turn into immune to the fungi. By genetically engineering fungi like Metarhizium anisopliae and Beauveria bassiana to delay the development of mosquito infectiousness the selection stress to evolve resistance is decreased. Another technique is to add proteins to the fungi that block transmission of malaria or remove the Plasmodium altogether. Most vaccines consist of viruses which have been attenuated, disabled, weakened or […]